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Diagnosis of Metachromatic Leukodystrophy, Krabbe Disease, and Farber Disease after Uptake of Fatty Acid-labeled Cerebroside Sulfate into Cultured Skin Fibroblasts

[(14)C]Stearic acid-labeled cerebroside sulfate (CS) was presented to cultured skin fibroblasts in the media. After endocytosis into control cells 86% was readily metabolized to galactosylceramide, ceramide, and stearic acid, which was reutilized in the synthesis of the major lipids found in culture...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kudoh, Tooru, Wenger, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1982
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC370230/
https://ncbi.nlm.nih.gov/pubmed/6806321
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