Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α

Mitochondrial biogenesis is an orchestrated process that presides to the regulation of the organelles homeostasis within a cell. We show that γ-rays, at doses commonly used in the radiation therapy for cancer treatment, induce an increase in mitochondrial mass and function, in response to a genotoxi...

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Detalhes bibliográficos
Main Authors: Bartoletti-Stella, A, Mariani, E, Kurelac, I, Maresca, A, Caratozzolo, M F, Iommarini, L, Carelli, V, Eusebi, L H, Guido, A, Cenacchi, G, Fuccio, L, Rugolo, M, Tullo, A, Porcelli, A M, Gasparre, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702280/
https://ncbi.nlm.nih.gov/pubmed/23764844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.187
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