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Repression of ATR pathway by miR-185 enhances radiation-induced apoptosis and proliferation inhibition
Cellular responses to DNA damage induced by intrinsic and extrinsic genotoxic stresses are highly regulated by complex signaling pathways, such as activation of the phosphoinositide-3-kinase-like protein kinase family and their downstream genes. Disruption of these signaling pathways leads to genome...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702279/ https://ncbi.nlm.nih.gov/pubmed/23807228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.227 |
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