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Islet Cell Surface Antibodies from Insulin-dependent Diabetics Bind Specifically to Pancreatic B Cells

Viable rat islet cells were used to detect islet cell surface antibodies (ICSA) in the sera of diabetic and control patients. ICSA were present in almost all recent-onset insulin-dependent diabetics younger than 30 yr (15/16); their incidence in other diabetics (6/22) was also higher than in normal...

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Udgivet i:J Clin Invest
Principais autores: Van De Winkel, M., Smets, G., Gepts, W., Pipeleers, D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1982
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370224/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6123526/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110601
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