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High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion

Vimentin is an intermediate filament protein, with a key role in the epithelial to mesenchymal transition as well as cell invasion, and it is often upregulated during cancer progression. However, relatively little is known about its regulation in cancer cells. Here, we performed an RNA interference...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lehtinen, Laura, Ketola, Kirsi, Mäkelä, Rami, Mpindi, John-Patrick, Viitala, Miro, Kallioniemi, Olli, Iljin, Kristiina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702207/
https://ncbi.nlm.nih.gov/pubmed/23295955
Tagiau: Ychwanegu Tag
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