Evidence Against Protective Role of Sex Hormone Estrogen in Cisplatin-Induced Nephrotoxicity in Ovarectomized Rat Model

BACKGROUND: Cisplatin (CP) is an effective drug in cancer therapy to treat the solid tumors, but it is accompanied with nephrotoxicity. The protective effect of estrogen in cardiovascular diseases is well-documented; but its nephron-protective effect against CP-induced nephrotoxicity is not complete...

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Autors principals: Pezeshki, Zahra, Nematbakhsh, Mehdi, Nasri, Hamid, Talebi, Ardeshir, Pilehvarian, Ali-Asghar, Safari, Tahereh, Eshraghi-Jazi, Fatemeh, Haghighi, Maryam, Ashrafi, Farzaneh
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications & Media Pvt Ltd 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702126/
https://ncbi.nlm.nih.gov/pubmed/23833437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-6580.111568
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