Potentiating Functional Antigen-specific CD8(+) T Cell Immunity by a Novel PD1 Isoform-based Fusion DNA Vaccine

Understanding and identifying new ways of mounting an effective CD8(+) T cell immune response is important for eliminating infectious pathogens. Although upregulated programmed death-1 (PD1) in chronic infections (such as HIV-1 and tuberculosis) impedes T cell responses, blocking this PD1/PD-L pathw...

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Detalhes bibliográficos
Main Authors: Zhou, Jingying, Cheung, Allen KL, Liu, Henggui, Tan, Zhiwu, Tang, Xian, Kang, Yuanxi, Du, Yanhua, Wang, Haibo, Liu, Li, Chen, Zhiwei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702111/
https://ncbi.nlm.nih.gov/pubmed/23587922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.63
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