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Potentiating Functional Antigen-specific CD8(+) T Cell Immunity by a Novel PD1 Isoform-based Fusion DNA Vaccine
Understanding and identifying new ways of mounting an effective CD8(+) T cell immune response is important for eliminating infectious pathogens. Although upregulated programmed death-1 (PD1) in chronic infections (such as HIV-1 and tuberculosis) impedes T cell responses, blocking this PD1/PD-L pathw...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702111/ https://ncbi.nlm.nih.gov/pubmed/23587922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.63 |
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