Role of calmodulin in platelet aggregation. Structure-activity relationship of calmodulin antagonists.
Two series of derivatives of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), including a dechlorinated analog of W-7 (W-5) and various aminoalkyl chain analogs of W-7 (A-3, A-4, A-5, I-240, A-6) were synthesized and their structure-activity relationships with calmodulin antagonistic action...
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| Publicado en: | J Clin Invest |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1982
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370207/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7085878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110574 |
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