Notch1 regulates angio-supportive bone marrow–derived cells in mice: relevance to chemoresistance

Host responses to chemotherapy can induce resistance mechanisms that facilitate tumor regrowth. To determine the contribution of bone marrow–derived cells (BMDCs), we exposed tumor-bearing mice to chemotherapeutic agents and evaluated the influx and contribution of a genetically traceable subpopulat...

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Autori principali: Roodhart, Jeanine M. L., He, Huanhuan, Daenen, Laura G. M., Monvoisin, Arnaud, Barber, Chad L., van Amersfoort, Miranda, Hofmann, Jennifer J., Radtke, Freddy, Lane, Timothy F., Voest, Emile E., Iruela-Arispe, M. Luisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2013
Soggetti:
Vascular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701902/
https://ncbi.nlm.nih.gov/pubmed/23690447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-11-459347
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