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TNF-induced death signaling triggers alveolar epithelial dysfunction in acute lung injury

The ability of the alveolar epithelium to prevent and resolve pulmonary edema is a crucial determinant of morbidity and mortality in acute lung injury (ALI). Tumor necrosis factor (TNF) has been implicated in ALI pathogenesis, but the precise mechanisms remain undetermined. We evaluated the role of...

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Detalhes bibliográficos
Main Authors: Patel, Brijesh V, Wilson, Michael R, O’Dea, Kieran, Takata, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701855/
https://ncbi.nlm.nih.gov/pubmed/23487422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202437
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