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Developing Therapeutic Antibodies for Neurodegenerative Disease

The central nervous system has been considered off-limits to antibody therapeutics. However, recent advances in preclinical and clinical drug development suggest that antibodies can cross the blood–brain barrier in limited quantities and act centrally to mediate their effects. In particular, immunot...

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Detalhes bibliográficos
Main Authors: Yu, Y. Joy, Watts, Ryan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701773/
https://ncbi.nlm.nih.gov/pubmed/23549647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0187-4
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