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Protein backbone and sidechain torsion angles predicted from NMR chemical shifts using artificial neural networks

A new program, TALOS-N, is introduced for predicting protein backbone torsion angles from NMR chemical shifts. The program relies far more extensively on the use of trained artificial neural networks than its predecessor, TALOS+. Validation on an independent set of proteins indicates that backbone t...

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Autori principali: Shen, Yang, Bax, Ad
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701756/
https://ncbi.nlm.nih.gov/pubmed/23728592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-013-9741-y
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