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Role for Endogenous and Acquired Peroxidase in the Toxoplasmacidal Activity of Murine and Human Mononuclear Phagocytes

Oxygen products generated by the respiratory burst of mononuclear phagocytes are microbicidal to intracellular pathogens including Toxoplasma gondii. The toxicity of one of these products, H(2)O(2), is markedly amplified by the granule peroxidase of circulating phagocytes in the presence of a halide...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Locksley, Richard M., Wilson, Christopher B., Klebanoff, Seymour J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1982
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370174/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7068848/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110545
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