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Measuring ER stress and the unfolded protein response using mammalian tissue culture system
The endoplasmic reticulum (ER) functions to properly fold and process secreted and transmembrane proteins. Environmental and genetic factors that disrupt ER function cause an accumulation of misfolded and unfolded proteins in the ER lumen, a condition termed ER stress. ER stress activates a signalin...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701721/ https://ncbi.nlm.nih.gov/pubmed/21266244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-385114-7.00004-0 |
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