Engineering a More Thermostable Blue Light Photo Receptor Bacillus subtilis YtvA LOV Domain by a Computer Aided Rational Design Method

The ability to design thermostable proteins offers enormous potential for the development of novel protein bioreagents. In this work, a combined computational and experimental method was developed to increase the T (m) of the flavin mononucleotide based fluorescent protein Bacillus Subtilis YtvA LOV...

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Hauptverfasser: Song, Xiangfei, Wang, Yefei, Shu, Zhiyu, Hong, Jingbo, Li, Tong, Yao, Lishan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701716/
https://ncbi.nlm.nih.gov/pubmed/23861663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003129
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