The Interactomes of Influenza Virus NS1 and NS2 Proteins Identify New Host Factors and Provide Insights for ADAR1 Playing a Supportive Role in Virus Replication

Influenza A NS1 and NS2 proteins are encoded by the RNA segment 8 of the viral genome. NS1 is a multifunctional protein and a virulence factor while NS2 is involved in nuclear export of viral ribonucleoprotein complexes. A yeast two-hybrid screening strategy was used to identify host factors support...

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Autores principales: de Chassey, Benoît, Aublin-Gex, Anne, Ruggieri, Alessia, Meyniel-Schicklin, Laurène, Pradezynski, Fabrine, Davoust, Nathalie, Chantier, Thibault, Tafforeau, Lionel, Mangeot, Philippe-Emmanuel, Ciancia, Claire, Perrin-Cocon, Laure, Bartenschlager, Ralf, André, Patrice, Lotteau, Vincent
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701712/
https://ncbi.nlm.nih.gov/pubmed/23853584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003440
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