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DNA Methylation Impacts Gene Expression and Ensures Hypoxic Survival of Mycobacterium tuberculosis

DNA methylation regulates gene expression in many organisms. In eukaryotes, DNA methylation is associated with gene repression, while it exerts both activating and repressive effects in the Proteobacteria through largely locus-specific mechanisms. Here, we identify a critical DNA methyltransferase i...

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Detalhes bibliográficos
Main Authors: Shell, Scarlet S., Prestwich, Erin G., Baek, Seung-Hun, Shah, Rupal R., Sassetti, Christopher M., Dedon, Peter C., Fortune, Sarah M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701705/
https://ncbi.nlm.nih.gov/pubmed/23853579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003419
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