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Effective Blocking of the White Enhancer Requires Cooperation between Two Main Mechanisms Suggested for the Insulator Function

Chromatin insulators block the action of transcriptional enhancers when interposed between an enhancer and a promoter. In this study, we examined the role of chromatin loops formed by two unrelated insulators, gypsy and Fab-7, in their enhancer-blocking activity. To test for this activity, we select...

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Detalhes bibliográficos
Main Authors: Kyrchanova, Olga, Maksimenko, Oksana, Stakhov, Viacheslav, Ivlieva, Tatyana, Parshikov, Alexander, Studitsky, Vasily M., Georgiev, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701704/
https://ncbi.nlm.nih.gov/pubmed/23861668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003606
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