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Nourseothricin N-Acetyl Transferase: A Positive Selection Marker for Mammalian Cells

Development of Nourseothricin N-acetyl transferase (NAT) as a selection marker for mammalian cells is described. Mammalian cells are acutely susceptible to Nourseothricin, similar to the widely used drug Puromycin, and NAT allows for quick and robust selection of transfected/transduced cells in the...

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Autors principals: Kochupurakkal, Bose S., Iglehart, J. Dirk
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701686/
https://ncbi.nlm.nih.gov/pubmed/23861913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068509
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