Nonstructural 5A Protein of Hepatitis C Virus Interacts with Pyruvate Carboxylase and Modulates Viral Propagation

Hepatitis C virus (HCV) is highly dependent on cellular factors for its own propagation. By employing tandem affinity purification method, we identified pyruvate carboxylase (PC) as a cellular partner for NS5A protein. NS5A interacted with PC through the N-terminal region of NS5A and the biotin carb...

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Bibliografiske detaljer
Main Authors: Yim, Seung-Ae, Lim, Yun-Sook, Kim, Jong-Wook, Hwang, Soon B.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701667/
https://ncbi.nlm.nih.gov/pubmed/23861867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068170
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