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Pre-Transplant CDKN2A Expression in Kidney Biopsies Predicts Renal Function and Is a Future Component of Donor Scoring Criteria

CDKN2A is a proven and validated biomarker of ageing which acts as an off switch for cell proliferation. We have demonstrated previously that CDKN2A is the most robust and the strongest pre-transplant predictor of post- transplant serum creatinine when compared to “Gold Standard” clinical factors, s...

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Detalhes bibliográficos
Main Authors: Gingell-Littlejohn, Marc, McGuinness, Dagmara, McGlynn, Liane M., Kingsmore, David, Stevenson, Karen S., Koppelstaetter, Christian, Clancy, Marc J., Shiels, Paul G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701657/
https://ncbi.nlm.nih.gov/pubmed/23861858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068133
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