Tanshinone IIA Increases the Bystander Effect of Herpes Simplex Virus Thymidine Kinase/Ganciclovir Gene Therapy via Enhanced Gap Junctional Intercellular Communication

The bystander effect is an intriguing phenomenon by which adjacent cells become sensitized to drug treatment during gene therapy with herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/GCV). This effect is reported to be mediated by gap junctional intercellular communication (GJIC), and there...

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Detalhes bibliográficos
Main Authors: Xiao, Jianyong, Zhang, Guangxian, Qiu, Pengxiang, Liu, Xijuan, Wu, Yingya, Du, Biaoyan, Li, Jiefen, Zhou, Jing, Li, Jingjing, Tan, Yuhui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701623/
https://ncbi.nlm.nih.gov/pubmed/23861780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067662
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