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Pharmacokinetics of Protein C and Antithrombin in the Fetal Lamb: A Model to Predict Human Neonatal Replacement Dosing
BACKGROUND: The preterm infant is at risk for consumptive coagulopathy and thrombosis due to late maturation of coagulation regulatory proteins. Replacement proteins are available, but neonatal pharmacokinetic data are lacking. OBJECTIVE: The objective was to determine the pharmacokinetic properties...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
S. Karger AG
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701438/ https://ncbi.nlm.nih.gov/pubmed/19039246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000178025 |
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