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Complex Rhythmicity and Age Dependence of Growth Hormone Secretion Are Preserved in Patients With Acromegaly: Further Evidence for a Present Hypothalamic Control of Pituitary Somatotropinomas

CONTEXT: Traditionally, acromegaly is viewed as a disease resulting from GH hypersecretion from an autonomous pituitary somatotropinoma. OBJECTIVE: To test the hypothesis that GH secretion in acromegaly is still subjected to normal hypothalamic control, we studied the daily rhythmicity of GH secreti...

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Autors principals: Ribeiro-Oliveira, Antônio, Abrantes, Marcelo Militão, Barkan, Ariel L.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701276/
https://ncbi.nlm.nih.gov/pubmed/23640965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-1581
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