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Divergent Expression of IL-1 Receptor Antagonists in CD34(+) Fibrocytes and Orbital Fibroblasts in Thyroid-associated Ophthalmopathy: Contribution of Fibrocytes to Orbital Inflammation

CONTEXT: Thyroid-associated ophthalmopathy (TAO) manifests as inflammation of orbital connective tissue. Bone marrow–derived CD34(+) fibrocytes infiltrate the orbit in TAO where they become CD34(+) orbital fibroblasts. They express thyroid-specific antigens and thus may contribute to inflammation. E...

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Detalhes bibliográficos
Main Authors: Li, Bin, Smith, Terry J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701275/
https://ncbi.nlm.nih.gov/pubmed/23633206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-1245
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