Norepinephrine transporter variant A457P knock-in mice display key features of human postural orthostatic tachycardia syndrome

Postural orthostatic tachycardia syndrome (POTS) is a common autonomic disorder of largely unknown etiology that presents with sustained tachycardia on standing, syncope and elevated norepinephrine spillover. Some individuals with POTS experience anxiety, depression and cognitive dysfunction. Previo...

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Detalhes bibliográficos
Main Authors: Shirey-Rice, Jana K., Klar, Rebecca, Fentress, Hugh M., Redmon, Sarah N., Sabb, Tiffany R., Krueger, Jessica J., Wallace, Nathan M., Appalsamy, Martin, Finney, Charlene, Lonce, Suzanna, Diedrich, André, Hahn, Maureen K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701219/
https://ncbi.nlm.nih.gov/pubmed/23580201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.012203
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