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The effect of hypoxia on facial shape variation and disease phenotypes in chicken embryos

Craniofacial anomalies can arise from both genetic and environmental factors, including prenatal hypoxia. Recent clinical evidence correlates hypoxia to craniofacial malformations. However, the mechanisms by which hypoxia mediates these defects are not yet understood. We examined the cellular mechan...

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Autors principals: Smith, Francis, Hu, Diane, Young, Nathan M., Lainoff, Alexis J., Jamniczky, Heather A., Maltepe, Emin, Hallgrimsson, Benedikt, Marcucio, Ralph S.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Limited 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701211/
https://ncbi.nlm.nih.gov/pubmed/23592613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.011064
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