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Sex-lethal promotes nuclear retention of msl2 mRNA via interactions with the STAR protein HOW

Female-specific repression of male-specific-lethal-2 (msl2) mRNA in Drosophila melanogaster provides a paradigm for coordinated control of gene expression by RNA-binding complexes. Repression is orchestrated by Sex-lethal (SXL), which binds to the 5′ and 3′ untranslated regions (UTRs) of the mRNA an...

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Autors principals: Graindorge, Antoine, Carré, Clément, Gebauer, Fátima
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701196/
https://ncbi.nlm.nih.gov/pubmed/23788626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.214999.113
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