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The CRTH2 agonist Pyl A prevents lipopolysaccharide-induced fetal death but induces preterm labour

We have previously demonstrated that the anti-inflammatory prostaglandin 15-deoxy-Δ 12,14-prostaglandin J(2) (15dPGJ(2)) delays inflammation-induced preterm labour in the mouse and improves pup survival through the inhibition of nuclear factor-κB (NF-κB) by a mechanism yet to be elucidated. 15dPGJ(2...

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Autores principales: Sykes, Lynne, Herbert, Bronwen R, MacIntyre, David A, Hunte, Emma, Ponnampalam, Sathana, Johnson, Mark R, Teoh, Tiong G, Bennett, Phillip R
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701182/
https://ncbi.nlm.nih.gov/pubmed/23374103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12085
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