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An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium
The extracellular matrix has a crucial role in determining the spatial orientation of epithelial polarity and the formation of lumens in glandular tissues, however the underlying mechanisms remain elusive. By using Cre-Lox deletion we show that β1-integrins are required for normal mammary gland morp...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701152/ https://ncbi.nlm.nih.gov/pubmed/23263281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2646 |
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