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Mutant Ubiquitin Attenuates Interleukin-1β- and Tumor Necrosis Factor-α-Induced Pro-Inflammatory Signaling in Human Astrocytic Cells

A frameshift mutation of ubiquitin called ubiquitin(+1) (UBB(+1)) was found in the aging and Alzheimer’s disease brains and thought to be associated with neuronal dysfuction and degeneration. Even though ubiquitylation has been known to regulate vital cellular functions mainly through proteasome-dep...

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Sonraí Bibleagrafaíochta
Main Authors: Choi, Kyungsun, Park, Junseong, Lee, Jungsul, Han, Eun Chun, Choi, Chulhee
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700915/
https://ncbi.nlm.nih.gov/pubmed/23844119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067891
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