Retrovirus transduction: generation of infectious retroviruses expressing dominant and selectable genes is associated with in vivo recombination and deletion events.

We describe the generation of infectious retroviruses containing foreign genes by an in vivo recombination-deletion mechanism. Cotransfection into mouse cells of chimeric plasmids carrying a murine retrovirus 5' long terminal repeat and either the thymidine kinase (tk) gene of herpesvirus or th...

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Detalles Bibliográficos
Main Authors: Joyner, A L, Bernstein, A
Formato: Artigo
Idioma:Inglês
Publicado: 1983
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC370089/
https://ncbi.nlm.nih.gov/pubmed/6318087
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