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Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53.

The steady-state levels of p53 protein and p53 mRNA in transformed and nontransformed cells were examined to elucidate the mechanisms controlling expression of p53. mRNA levels were determined by Northern blot hybridization analysis, employing a p53-specific cDNA clone (M. Oren and A.J. Levine, Proc...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Reich, N C, Oren, M, Levine, A J
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1983
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370084/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6318085/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.3.12.2143-2150.1983
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