Randomized phase I pharmacokinetic study of ipilimumab with or without one of two different chemotherapy regimens in patients with untreated advanced melanoma

We describe a randomized three-arm phase I study of ipilimumab administered alone (I group) or in combination with dacarbazine (D group) or carboplatin/paclitaxel (CP group) in patients with previously untreated advanced melanoma. The primary objective was to estimate the effect of ipilimumab on the...

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Autors principals: Weber, Jeffrey, Hamid, Omid, Amin, Asim, O’Day, Steven, Masson, Eric, Goldberg, Stacie M., Williams, Daphne, Parker, Susan M., Chasalow, Scott D., Alaparthy, Suresh, Wolchok, Jedd D.
Format: Artigo
Idioma:Inglês
Publicat: Academy of Cancer Immunology 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700777/
https://ncbi.nlm.nih.gov/pubmed/23833564
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