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Properties of single-step mutants of Syrian hamster cell lines resistant to N-(phosphonacetyl)-L-aspartate.

Eleven independent lines of Syrian hamster cells were selected by using very low levels of N-(phosphonacetyl)-L-aspartate (PALA), an inhibitor of aspartate transcarbamylase. The protocol employed insured that each resistant cell arose during one of the last divisions before selection was applied. Ce...

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Bibliographic Details
Main Authors: Zieg, J, Clayton, C E, Ardeshir, F, Giulotto, E, Swyryd, E A, Stark, G R
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC370075/
https://ncbi.nlm.nih.gov/pubmed/6656764
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