Effects of radiation on the epidermal growth factor receptor pathway in the heart

PURPOSE: Radiation-induced heart disease (RIHD) is a serious side effect of thoracic radiotherapy. The epidermal growth factor receptor (EGFR) pathway is essential for the function and survival of cardiomyocytes. Hence, agents that target the EGFR pathway are cardiotoxic. Tocotrienols protect from r...

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Hauptverfasser: Sridharan, Vijayalakshmi, Sharma, Sunil K., Moros, Eduardo G., Corry, Peter M., Tripathi, Preeti, Lieblong, Benjamin J., Guha, Chandan, Hauer-Jensen, Martin, Boerma, Marjan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700655/
https://ncbi.nlm.nih.gov/pubmed/23488537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09553002.2013.782110
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