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PREPARATION, DRUG RELEASE, AND CELL GROWTH INHIBITION OF A GELATIN – DOXORUBICIN CONJUGATE
PURPOSE: To demonstrate the feasibility of a novel macromolecular delivery system for doxorubicin (DOX) which combines pH dependent DOX release with a high molecular weight and biodegradable gelatin carrier. METHODS: DOX was conjugated to gelatin using an acid labile hydrazone bond and a glycylglyci...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3700642/ https://ncbi.nlm.nih.gov/pubmed/23686374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1065-9 |
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