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A Neu View of Invasive Lobular Breast Cancer
Genome sequencing of relapsed, invasive lobular breast cancer identified actionable mutations in 86% of cases. HER2 alterations occur in 27% of cases, including four cases with activating HER2 mutations and one with a novel HER2-GRB7 gene fusion. This fusion links the HER2 tyrosine kinase domain to...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3700640/ https://ncbi.nlm.nih.gov/pubmed/23714731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1031 |
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