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Properties of asparagine synthetase in asparagine-independent variants of Jensen rat sarcoma cells induced by 5-azacytidine.

Jensen rat sarcoma cells in culture require L-asparagine for growth and lack detectable levels of asparagine synthetase. Cultures exposed for 24 h to graded concentrations of 5-azacytidine give rise to asparagine-independent variants in high frequency. These prototrophs are stable phenotypically whe...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Autores principales: Sugiyama, R H, Arfin, S M, Harris, M
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1983
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370060/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6197624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.3.11.1937-1942.1983
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