Clinical activity and safety of combination therapy with temsirolimus and bevacizumab for advanced melanoma: A Phase II trial (CTEP 7190/Mel47)

PURPOSE: A CTEP-sponsored phase II trial was performed to evaluate safety and clinical activity of combination therapy with CCI-779 (temsirolimus) and bevacizumab in patients with advanced melanoma. EXPERIMENTAL DESIGN: Patients with unresectable stage III to IV melanoma were treated intravenously w...

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Detalhes bibliográficos
Main Authors: Slingluff, Craig L., Petroni, Gina R, Molhoek, Kerrington R., Brautigan, David L., Chianese-Bullock, Kimberly A., Shada, Amber L., Smolkin, Mark E., Olson, Walter C., Gaucher, Alison, Chase, Cheryl Murphy, Grosh, William W., Weiss, Geoffrey R., Wagenseller, Aubrey G., Olszanski, Anthony J., Martin, Lainie, Shea, Sofa M., Erdag, Gulsun, Ram, Prahlad, Gershenwald, Jeffrey E., Weber, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700572/
https://ncbi.nlm.nih.gov/pubmed/23620404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3919
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