Clinical activity and safety of combination therapy with temsirolimus and bevacizumab for advanced melanoma: A Phase II trial (CTEP 7190/Mel47)

PURPOSE: A CTEP-sponsored phase II trial was performed to evaluate safety and clinical activity of combination therapy with CCI-779 (temsirolimus) and bevacizumab in patients with advanced melanoma. EXPERIMENTAL DESIGN: Patients with unresectable stage III to IV melanoma were treated intravenously w...

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Main Authors: Slingluff, Craig L., Petroni, Gina R, Molhoek, Kerrington R., Brautigan, David L., Chianese-Bullock, Kimberly A., Shada, Amber L., Smolkin, Mark E., Olson, Walter C., Gaucher, Alison, Chase, Cheryl Murphy, Grosh, William W., Weiss, Geoffrey R., Wagenseller, Aubrey G., Olszanski, Anthony J., Martin, Lainie, Shea, Sofa M., Erdag, Gulsun, Ram, Prahlad, Gershenwald, Jeffrey E., Weber, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700572/
https://ncbi.nlm.nih.gov/pubmed/23620404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3919
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