Hyperphagia and Increased Fat Accumulation in Two Models of Chronic CNS Glucagon-Like Peptide-1 Loss of Function

Central administration of glucagon-like peptide-1 (GLP-1) causes a dose-dependent reduction in food intake, but the role of endogenous CNS GLP-1 in the regulation of energy balance remains unclear. Here, we tested the hypothesis that CNS GLP-1 activity is required for normal energy balance by using...

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Main Authors: Barrera, Jason G., Jones, Kenneth R., Herman, James P., D'Alessio, David A., Woods, Stephen C., Seeley, Randy J.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2011
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700400/
https://ncbi.nlm.nih.gov/pubmed/21389245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2212-10.2011
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