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A Novel Flex-Stretch-Flow Bioreactor for the Study of Engineered Heart Valve Tissue Mechanobiology

Tissue engineered heart valves (TEHV) have been observed to respond to mechanical conditioning in vitro by expression of activated myofibroblast phenotypes followed by improvements in tissue maturation. In separate studies, cyclic flexure, stretch, and flow (FSF) have been demonstrated to exhibit bo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Engelmayr, George C., Soletti, Lorenzo, Vigmostad, Sarah C., Budilarto, Stephanus G., Federspiel, William J., Chandran, Krishnan B., Vorp, David A., Sacks, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700375/
https://ncbi.nlm.nih.gov/pubmed/18253834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-008-9447-6
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