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Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster

KFase (kynurenine formamidase), also known as arylformamidase and formylkynurenine formamidase, efficiently catalyses the hydrolysis of NFK (N-formyl-L-kynurenine) to kynurenine. KFase is the second enzyme in the kynurenine pathway of tryptophan metabolism. A number of intermediates formed in the ky...

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Detalles Bibliográficos
Main Authors: Han, Qian, Robinson, Howard, Li, Jianyong
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700353/
https://ncbi.nlm.nih.gov/pubmed/22690733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120416
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