Molecular Evolution of the HIV-1 Thai Epidemic between the Time of RV144 Immunogen Selection to the Execution of the Vaccine Efficacy Trial

The RV144 HIV-1 vaccine trial (Thailand, 2003 to 2009), using immunogens genetically matched to the regional epidemic, demonstrated the first evidence of efficacy for an HIV-1 vaccine. Here we studied the molecular evolution of the HIV-1 epidemic from the time of immunogen selection to the execution...

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Detalhes bibliográficos
Main Authors: Kijak, Gustavo H., Tovanabutra, Sodsai, Rerks-Ngarm, Supachai, Nitayaphan, Sorachai, Eamsila, Chirapa, Kunasol, Prayura, Khamboonruang, Chirasak, Thongcharoen, Prasert, Namwat, Chawetsan, Premsri, Nakorn, Benenson, Michael, Morgan, Patricia, Bose, Meera, Sanders-Buell, Eric, Paris, Robert, Robb, Merlin L., Birx, Deborah L., De Souza, Mark S., McCutchan, Francine E., Michael, Nelson L., Kim, Jerome H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700312/
https://ncbi.nlm.nih.gov/pubmed/23576510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03070-12
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