Genetic Requirement for Hemagglutinin Glycosylation and Its Implications for Influenza A H1N1 Virus Evolution

Influenza A virus has evolved and thrived in human populations. Since the 1918 influenza A pandemic, human H1N1 viruses had acquired additional N-linked glycosylation (NLG) sites within the globular head region of hemagglutinin (HA) until the NLG-free HA head pattern of the 1918 H1N1 virus was renew...

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Autors principals: Kim, Jin Il, Lee, Ilseob, Park, Sehee, Hwang, Min-Woong, Bae, Joon-Yong, Lee, Sangmoo, Heo, Jun, Park, Mee Sook, García-Sastre, Adolfo, Park, Man-Seong
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Genetic Diversity and Evolution
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700310/
https://ncbi.nlm.nih.gov/pubmed/23637398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00373-13
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