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A Conserved Gammaherpesvirus Protein Kinase Targets Histone Deacetylases 1 and 2 To Facilitate Viral Replication in Primary Macrophages

Gammaherpesviruses are ubiquitious pathogens that establish lifelong infection and are associated with several malignancies. All gammaherpesviruses encode a conserved protein kinase that facilitates viral replication and chronic infection and thus represents an attractive therapeutic target. In this...

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Hlavní autoři: Mounce, Bryan C., Mboko, Wadzanai P., Bigley, Tarin M., Terhune, Scott S., Tarakanova, Vera L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700300/
https://ncbi.nlm.nih.gov/pubmed/23616648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02713-12
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