Upregulation of CHOP/GADD153 during Coronavirus Infectious Bronchitis Virus Infection Modulates Apoptosis by Restricting Activation of the Extracellular Signal-Regulated Kinase Pathway

Induction of the unfolded protein response (UPR) is an adaptive cellular response to endoplasmic reticulum (ER) stress that allows a cell to reestablish ER homeostasis. However, under severe and persistent ER stress, prolonged UPR may activate unique pathways that lead to cell death. In this study,...

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Bibliographische Detailangaben
Hauptverfasser: Liao, Ying, Fung, To Sing, Huang, Mei, Fang, Shou Guo, Zhong, Yanxin, Liu, Ding Xiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Cellular Response to Infection
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700216/
https://ncbi.nlm.nih.gov/pubmed/23678184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00626-13
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