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Analysis of the Role of Vaccinia Virus H7 in Virion Membrane Biogenesis with an H7-Deletion Mutant

Essential vaccinia virus genes are often studied with conditional-lethal inducible mutants. Here, we constructed a deletion mutant lacking the essential H7R gene (the ΔH7 mutant) with an H7-expressing cell line. Compared to an inducible H7 mutant, the ΔH7 mutant showed a defect at an earlier step of...

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Hlavní autoři: Meng, Xiangzhi, Wu, Xiang, Yan, Bo, Deng, Junpeng, Xiang, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700178/
https://ncbi.nlm.nih.gov/pubmed/23678177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00845-13
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