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Synthesis and Biological Activity of New Thiopyrano[2,3-d]thiazoles Containing a Naphthoquinone Moiety

Novel 11-substituted 3,11-dihydro-2H-benzo[6,7]thiochromeno[2,3-d][1,3]-thiazole-2,5,10-triones 4a–i were synthesized in 75–90% yields via the hetero-Diels-Alder reaction of 5-arylidene-4-thioxo-2-thiazolidinones with 1,4-naphthoquinone. The synthesized compounds were evaluated for their antineoplas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Atamanyuk, Dmytro, Zimenkovsky, Borys, Atamanyuk, Vasyl, Nektegayev, Ihor, Lesyk, Roman
Format: Artigo
Sprache:Inglês
Veröffentlicht: Österreichische Apotheker-Verlagsgesellschaft 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700073/
https://ncbi.nlm.nih.gov/pubmed/23833711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1301-13
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