Synthesis, Structural Elucidation, and In Vitro Antitumor Activities of Some Pyrazolopyrimidines and Schiff Bases Derived from 5-Amino-3-(arylamino)-1H-pyrazole-4-carboxamides

The reaction of 5-amino-3-(arylamino)-1H-pyrazole-4-carboxamides 1a,b with acetylacetone 2 and arylidenemalononitriles 5a–c yielded the pyrazolo[1,5-a]-pyrimidine derivatives 4a,b and 7a–f respectively. On the other hand, Schiff bases 9a,b and 12a–j were obtained upon treatment of carboxamides 1a,b...

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Main Authors: Hafez, Taghrid S., Osman, Souad A., Yosef, Hisham Abdallah A., El-All, Amira S. Abd, Hassan, Ashraf S., El-Sawy, Abdallah A., Abdallah, Mohamed M., Youns, Mahmoud
Formato: Artigo
Idioma:Inglês
Publicado em: Österreichische Apotheker-Verlagsgesellschaft 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700070/
https://ncbi.nlm.nih.gov/pubmed/23833708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1211-07
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